Detection of Anal Dysplasia by Chromoendoscopy with Narrow Band Imaging and Acetic Acid (NBIA) in 182 Patients

Michelle D Inkster and James S Wu

Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA

^*Correspondance to: James S Wu 

 PDF  Full Text DOI: 10.25107/2474-1647.1583

Abstract

Anal squamous intraepithelial lesion (SIL) precedes the development of anal squamous cell carcinoma (SCC). Detection of SIL is facilitated by chromoendoscopy with narrow band imaging and acetic acid (NBIA). Between 2011 and 2017, 182 patients with abnormal anal cytology underwent NBIA to identify and ablate SIL. The majority of patients were HIV positive men. Other associated diagnoses included urogynecologic dysplasia, inflammatory bowel disease and organ transplantation. The histopathologic diagnosis of SIL/SCC was found in 65% of cases overall (52% for cytology showing atypical cells, 81% for cytology showing low-grade SIL and 73% for cytology showing high-grade SIL). Illustrative examples showing the endoscopic appearance of LSIL, HSIL, and SCC are shown. The procedure can be done in any facility where endoscopy is practiced.

Keywords

Squamous intraepithelial neoplasia; Chromoendoscopy; Narrow band imaging; Human papillomavirus; Human immunodeficiency virus; Organ transplantation; Inflammatory bowel disease

Cite the article

Inkster MD, Wu JS. Detection of Anal Dysplasia by Chromoendoscopy with Narrow Band Imaging and Acetic Acid (NBIA) in 182 Patients. Clin Surg. 2017; 2: 1583.