Clin Surg | Volume 2, Issue 1 | Case Report | Open Access

Mesenchymal Stem Cell Allograft in a Nonunion Fibular Fracture: A Case Report

Brett D Sachs1* and Kaitlyn Bernhard2

1Departemnt of Podiatric Surgery, Presbyterian St. Luke’s Medical Center, USA
2Deprtment of Podiatric Medicine and Surgery, Presbyterian St. Luke’s Medical Center, USA

*Correspondance to: Brett D Sachs 

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Abstract

Ankle fractures are common injuries treated by the foot and ankle surgeon. The majority of stable, uncomplicated, minimally or non-displaced distal fibular fractures will heal with adequate immobilization and conservative treatment. However, some patients will develop a symptomatic partial union or nonunion. Several factors can contribute to a nonunion following a fracture including smoking, obesity, infection, and diabetes mellitus. In cases of surgical reconstruction, augmentation with osteobiologics consisting of mesenchymal stem cells can be utilized to enhance osseous healing of the nonunion site. We present a successful case of a distal fibular nonunion repair with the use of a partially demineralized allograft bone combined with adipose derived mesenchymal stem cells to promote bone healing. At six months follow-up, there was solid bone healing of the fibular nonunion with complete resolution of symptoms.

Citation:

Sachs BD, Bernhard K. Mesenchymal Stem Cell Allograft in a Nonunion Fibular Fracture: A Case Report. Clin Surg. 2017; 2: 1395.

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