Edward H Tsoi1,2*, Georgina R Cameron1,2, Paul V Desmond1,2 and Andrew CF Taylor1,2
1Departemnt of Gastroenterology, St Vincent’s Hospital Melbourne, Melbourne, Victoria, Australia
2Departemnt of Gastroenterology University of Melbourne, Melbourne, Victoria, Australia
There are multiple international guidelines on the management of non dysplastic Barrett’s oesophagus (NDBE) and Barrett’s oesophagus with high grade dysplasia (HGD). Despite the numerous studies in the literature pertaining to the management of Barrett’s oesophagus with low grade dysplasia (LGD), there is still no agreement due to the lack of evidence in respect to the diagnosis, progression rate and best management of Barrett’s oesophagus with LGD. This review discusses the current controversies in the management of LGD, including surveillance intervals and techniques, effectiveness and safety of radiofrequency ablation (RFA), cost effectiveness of RFA, natural history of LGD, and risk factors for progression from LGD to HGD or oesophageal adenocarcinoma (OAC), and ultimately addressing the ideal management strategy for patients with Barrett’s oesophagus with LGD.
Tsoi EH, Cameron GR, Desmond PV, Taylor ACF. Addressing Controversies in the Management of Barrett's Oesophagus with Low Grade Dysplasia. Clin Surg. 2017; 2: 1391.