Clin Surg | Volume 1, Issue 1 | Case Report | Open Access

Metachronous Bladder Metastasis from Clear Cell Renal Cell Carcinoma

Terence Chun-ting Lai and Ming-kwong Yiu*

Department of Surgery, Division of Urology, University of Hong Kong, China

*Correspondance to: Ming-kwong Yiu 

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Bladder metastasis, either synchronous or metachronous, is an uncommon presentation of renal cell carcinoma. We herein report a metachronous bladder metastasis from renal cell carcinoma of clear cell type, and review the current literature on the presentation, management and prognosis of this kind of metastasis. A 77-year-old man was presented to Queen Mary Hospital, Hong Kong in 2011 with hematuria, subsequently found a renal tumor invading into renal pelvis. Open right radical nephrectomy was performed and the tumor was confirmed to be pT1b clear cell carcinoma of Fuhrman grade 2. He remained asymptomatic all along after nephrectomy, but surveillance ultrasonography (USG) revealed a 2.2 cm bladder neck mass in 23 months after nephrectomy. After patient refused transurethral resection, the mass further enlarged to 3.8cm one year later. Transurethral resection was performed and histopathological examination confirmed clear cell carcinoma, with no fibro-muscular invasion. Multiple pulmonary metastases were also found on computed tomography (CT) of the thorax. He refused target therapy and preferred conservative treatment. He remained symptom-free 2 months after the transurethral resection.


Bladder metastasis; Renal cell carcinoma; Ultrasonography


Chun-ting Lai T, Yiu M-k. Metachronous Bladder Metastasis from Clear Cell Renal Cell Carcinoma. Clin Surg. 2016; 1: 1178.

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