A 48-Hour Regimen of Perioperative Antibiotic Prophylaxis in Laparoscopic-Assisted Radical Resection for Rectal Cancer: An Analysis of 124 Cases

Kaiyan Fu, Huanrong Lan, Ketao Jin and Hongying Pan

Department of Nursing, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, China
Department of General Surgery, Zhuji Hospital of Wenzhou Medical University, China
Department of Breast and Thyroid Surgery, Shaoxing Hospital of Zhejiang University, China
Department of Gastrointestinal Surgery, Shaoxing Hospital of Zhejiang University, China

^*Correspondance to: Ketao Jin 

 PDF  Full Text DOI: 10.25107/2474-1647.1132

Abstract

Objective: It is widely accepted that antibiotic prophylaxis is useful for the prevention of surgical site infections, especially in colorectal surgery. But the standard protocol of perioperative antibiotic use in laparoscopic-assisted surgery for rectal cancer remains to be established. To evaluate the rate of perioperative infections following rectal cancer surgery and to determine the time of using prophylactic antibiotic, we retrospectively reviewed the clinical data of 124 patients receiving laparoscopic-assisted radical resection for rectal cancer to investigate the occurrence of perioperative infections following laparoscopic surgery.
Methods: This study included 124 cases receiving laparoscopic-assisted radical resection of rectal cancer from January 2014 to December 2014. A 48-hour treatment of intravenous antibiotic prophylaxis was used. The incidence of incisional surgical site infection (SSI), organ/space SSI, and remote infection was retrospectively investigated.Results: The overall rate of SSIs following laparoscopic-assisted radical resection for rectal cancer was to be 13.71%. Incisional SSI occurred in 5 (4.03%) patients. Organ/space SSI occurred in 6 (4.84%) patients. Remote infection occurred in 6 (4.84%) patients.Conclusion: The incidence of incisional SSI, organ/space SSI and remote infection was low using a 48-hour treatment of intravenous antibiotic prophylaxis after laparoscopic-assisted radical resection for rectal cancer. Thus, a 48-hour treatment of intravenous antibiotic prophylaxis should be enough to prevent the emergence of antibiotic-resistant bacterial infection in laparoscopic-assisted radical resection for rectal cancer.

Keywords

Intravenous antimicrobial prophylaxis; Laparoscopic-assisted surgery; Rectal cancer; Surgical site infection (SSI); Remote infection

Cite the article

Fu K, Lan H, Jin K, Pan H. A 48-Hour Regimen of Perioperative Antibiotic Prophylaxis in Laparoscopic-Assisted Radical Resection for Rectal Cancer: An Analysis of 124 Cases. Clin Surg. 2016; 1: 1132.