Sara Cavallari, Tullio Piardi*, Ana Diaz Cives and Reza Kianmanesh
Department of General, Digestive and Endocrine Surgery, Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims, FranceFulltext PDF
Neuroendocrine tumors are cancers that develop in the diffuse neuroendocrine system. The small intestine is one of the most common sites where gastrointestinal neuroendocrine cancers develop and the most common histological types of malignant tumors of the small intestine. In the literature the relationship between neuroendocrine tumors and the development of secondary primary malignancies, whether synchronous or metachronous, is well described. Usually, these involve the colorectal, the gastro urinary tract and the bronco pulmonary system, while the localization in the small intestine is uncommon. We describe here the case of a patient followed-up for an ileal resection, which occurred in emergency for intestinal obstruction; the latter was due to a jejunal adenocarcinoma linked to a neuroendocrine tumor. This report illustrates the rare association of small intestinal neuroendocrine tumor with secondary small bowel malignancies.
Cavallari S, Piardi T, Cives AD, Kianmanesh R. Acute Intestinal Obstruction Revealing Metachronous Gastrointestinal Adenocarcinoma in a Small Bowel Neuroendocrine Tumor: A Case Report. Clin Surg. 2016; 1: 1022.